Week 3 · 16 games · September 21, 2025 · Updated Jul 9, 12:07 AM ET
The Almanac's Take
The headliner is DET-BAL at 53.5, the week's highest total, played outdoors in Baltimore at 74 degrees with just 7 mph of wind — nothing there to push that number down. MIA-BUF sits at 50.5 with similarly calm conditions, 68 degrees and 7 mph, so both big totals are playing in cooperative weather. The coolest outdoor spots are Seattle at 63 and Foxborough at 66, though neither game carries a total above 44.5, so the books already priced the conditions in. MIN-CIN and LAC-DEN are both indoors, weather non-factors. Across the full slate, wind is a non-issue — nothing cracks 11 mph.
Miami Dolphins at Buffalo Bills
Thu 8:15 PM ET
New Era Field
Conditions
OutdoorA-Turf68°F7 mph wind
Vegas line
BUF -12.5O/U 50.5
Atlanta Falcons at Carolina Panthers
Sun 1:00 PM ET
Bank of America Stadium
Conditions
OutdoorGrass83°F5 mph wind
Vegas line
ATL -5.5O/U 44.5
Cincinnati Bengals at Minnesota Vikings
Sun 1:00 PM ET
U.S. Bank Stadium
Conditions
IndoorsSportTurf
Vegas line
MIN -3O/U 41.5
Green Bay Packers at Cleveland Browns
Sun 1:00 PM ET
FirstEnergy Stadium
Conditions
OutdoorGrass79°F10 mph wind
Vegas line
GB -8.5O/U 41.5
Houston Texans at Jacksonville Jaguars
Sun 1:00 PM ET
TIAA Bank Stadium
Conditions
OutdoorGrass85°F11 mph wind
Vegas line
JAX -1.5O/U 43.5
Indianapolis Colts at Tennessee Titans
Sun 1:00 PM ET
Nissan Stadium
Conditions
OutdoorGrass84°F8 mph wind
Vegas line
IND -6O/U 43.5
Los Angeles Rams at Philadelphia Eagles
Sun 1:00 PM ET
Lincoln Financial Field
Conditions
OutdoorGrass73°F9 mph wind
Vegas line
PHI -3.5O/U 45.5
Las Vegas Raiders at Washington Commanders
Sun 1:00 PM ET
FedExField
Conditions
OutdoorGrass72°F6 mph wind
Vegas line
WAS -2.5O/U 43.5
New York Jets at Tampa Bay Buccaneers
Sun 1:00 PM ET
Raymond James Stadium
Conditions
OutdoorGrass88°F5 mph wind
Vegas line
TB -6.5O/U 43.5
Pittsburgh Steelers at New England Patriots
Sun 1:00 PM ET
Gillette Stadium
Conditions
OutdoorField Turf66°F5 mph wind
Vegas line
PIT -1.5O/U 44.5
Denver Broncos at Los Angeles Chargers
Sun 4:05 PM ET
SoFi Stadium
Conditions
IndoorsMatrixTurf
Vegas line
LAC -2.5O/U 45.5
New Orleans Saints at Seattle Seahawks
Sun 4:05 PM ET
Lumen Field
Conditions
OutdoorField Turf63°F3 mph wind
Vegas line
SEA -7.5O/U 41.5
Arizona Cardinals at San Francisco 49ers
Sun 4:25 PM ET
Levi's Stadium
Conditions
OutdoorGrass72°F7 mph wind
Vegas line
SF -1.5O/U 44.5
Dallas Cowboys at Chicago Bears
Sun 4:25 PM ET
Soldier Field
Conditions
OutdoorGrass82°F4 mph wind
Vegas line
DAL -1.5O/U 49.5
Kansas City Chiefs at New York Giants
Sun 8:20 PM ET
MetLife Stadium
Conditions
OutdoorField Turf65°F5 mph wind
Vegas line
KC -6O/U 44.5
Detroit Lions at Baltimore Ravens
Mon 8:15 PM ET
M&T Bank Stadium
Conditions
OutdoorGrass74°F7 mph wind
Vegas line
BAL -4.5O/U 53.5
Methodology
Conditions and venue come from the nflverse schedules feed. Temperature and wind are shown only when forecast — they are blank (never zero) for dome/closed-roof games and for outdoor games whose forecast hasn't posted yet. The spread is shown in favorite form; a positive home line in the source feed means the home team is favored. Lines are the market's, for context — not a betting recommendation.
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